
Drug discovery is broken.
Katamaran is fixing it.
95% of oncology drugs fail in clinical development
Traditional preclinical models often fail to predict how real human tumors respond. Cell lines and animal systems miss critical features of tumor biology, including microenvironment, architecture, and context.
Conventional models often do not translate to human patients (“The Mouse Trap”)

Al trained on this noise hallucinates better failures. Better biological data is essential for better prediction
Our R&D and Pipeline
We use AI to support target selection, indication prioritization, biomarker discovery, responder hypothesis generation, and therapeutic design across small molecules and biologics.
Predict
As our platform generates more proprietary human tumor data, we use those insights to improve models, standardize assays, expand throughput through automation and microfluidics, and build toward fine-tuned biological foundation models grounded in real human tumor biology.
Validate
We generate patient-derived tumoroids and ex vivo tissue models from fresh human tumor samples to evaluate drug response in a more biologically relevant setting, preserving key aspects of tumor architecture and microenvironment.
Scale
(Lab-in-the-Loop)
(The Ex-Vivo Edge)
(Al-Driven)






Katamaran is building a proprietary Gen 3 human-data engine for oncology drug discovery.
Our platform moves beyond public-data-only bio-AI by integrating proprietary multi-modal spatial human tumor datasets to build fine-tuned biological foundation models grounded in ex vivo human tumor data
Our Business


Our Company


Arun Asaithambi has been working at the intersection of AI and oncology drug discovery since 2013. As Founder and former CEO of Lantern Pharma [NASDAQ: LTRN], he helped pioneer early AI-driven drug development and is now building Katamaran’s next-generation platform.
Arun Asaithambi, Ph.D.
Founder and CEO
Anand Asaithambi,
Co-Founder



Research labs

- Arun Asaithambi, Ph.D.
Founder and CEO

October 10, 2017
October 10, 2017
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Featured News
Sep 26, 2023
Aug 01, 2025
October 10, 2017
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What Experts Are Saying

“Head and neck cancers are extremely common but low awareness and non-specific symptoms delay diagnosis. When caught early they have excellent cure rates. Precision therapies are becoming more crucial as a one size fits all approach is ineffective.”
-Dr. Narayana Subramaniam
Lead Consultant, Head & Neck Oncology, Aster Hospitals, Bangalore
Our Collaborators


We’re looking for collaborators, investors, and visionary scientists. Reach out and be part of the mission.









